CONTACT

Anne-Laure Papa, Ph.D.

Science and Engineering Hall,

800 22nd St NW, 

Washington, DC 20052

alpapa@gwu.edu

Tel 202-994-0627

Office hours: Thursdays 4:30 - 6:30pm

 

GW Biomedical Engineering:

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© 2019 by Anne-Laure Papa. Created with Wix.com

*corresponding authors; ** these authors have contributed equally to the work

 

  1. Papa AL*, Jiang A, Korin N, Chen MB, Langan ET, Waterhouse A, Nash E, Caroff J, Graveline A, Vernet A, Mammoto A, Mammoto T, Jain A, Kamm RD, Gounis MJ, Ingber DE*. Platelet Decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models. Science Translational Medicine. 2019, http://stm.sciencemag.org/content/11/479/eaau5898                            Press releases: https://www.sciencemag.org/news/2019/02/these-platelet-decoys-could-prevent-blood-clots-without-spreading-cancerhttps://wyss.harvard.edu/platelet-decoys-outsmart-both-clots-and-cancer/https://mediarelations.gwu.edu/researchers-develop-reversible-drug-free-antiplatelet-therapy-fight-dangerous-blood-clots-and-cancer

  2. Papa AL, Korin N, Kanapathipillai M, Mammoto A, Mammoto T, Jiang A, Mannix R, Uzun O, Johnson C, Bhatta D, Cuneo G, Ingber DE*. Ultrasound-sensitive nanoparticle aggregates for targeted drug delivery. Biomaterials. 2017;139:187-94. https://www.ncbi.nlm.nih.gov/pubmed/28618348

  3. Jain A, van der Meer AD, Papa AL, Barrile R, Lai A, Schlechter BL, Otieno MA, Louden CS, Hamilton GA, Michelson A, Frelinger 3rd AL, Ingber DE*. Assessing Hemostasis and Platelet Function using a Microfluidic Device Lined with a Fixed Human Endothelium. Biomedical Microdevices. 2016(18):73. https://www.ncbi.nlm.nih.gov/pubmed/27464497

  4. Maurizi L, Papa AL, Dumont L, Bouyer F, Walker P, Vandroux D, Millot N*. Influence of surface charge and polymer coating on internalization and biodistribution of PEG-modified iron oxide nanoparticles. Journal of Biomedical Nanotechnology. 2015;11(1):126-36. http://www.ingentaconnect.com/content/asp/jbn/2015/00000011/00000001/art00009

  5. Papa AL**, Boudon J**, Bellat V, Loiseau A, Bisht H, Sallem F, Chassagnon R, Berard V, Millot N*. Dispersion of titanate nanotubes for nanomedicine: comparison of PEI and PEG nanohybrids. Dalton Trans. 2015;44(2):739-46. http://www.ncbi.nlm.nih.gov/pubmed/25408156

  6. Marosfoi MG, Korin N, Gounis MJ, Uzun O, Vedantham S, Langan ET, Papa AL, Brooks OW, Johnson C, Puri AS, Bhatta D, Kanapathipillai M, Bronstein BR, Chueh JY, Ingber DE, Wakhloo AK*. Shear-Activated Nanoparticle Aggregates Combined With Temporary Endovascular Bypass to Treat Large Vessel Occlusion. Stroke. 2015;46(12):3507-13. http://www.ncbi.nlm.nih.gov/pubmed/26493676

  7. Pandey A, Sarangi S, Chien K, Sengupta P, Papa AL, Basu S, Siddiqui A, Sengupta S*. Anti-platelet agents augment cisplatin nanoparticle cytotoxicity by enhancing tumor vasculature permeability and drug delivery. Nanotechnology. 2014;25(44):445101. http://iopscience.iop.org/0957-4484/25/44/445101

  8. Papa AL, Dumont L, Vandroux D, Millot N*. Titanate nanotubes: towards a novel and safer nanovector for cardiomyocytes. Nanotoxicology. 2013;7(6):1131-42. http://www.ncbi.nlm.nih.gov/pubmed/22770363

  9. Sarangi S, Pandey A, Papa AL, Sengupta P, Kopparam J, Dadwal U, Basu S, Sengupta S*. P2Y12 receptor inhibition augments cytotoxic effects of cisplatin in breast cancer. Medical Oncology. 2013;30(2):567. http://www.ncbi.nlm.nih.gov/pubmed/23568163

  10. Papa AL, Sidiqui A, Balasubramanian SU, Sarangi S, Luchette M, Sengupta S*, Harfouche R*. PEGylated liposomal Gemcitabine: insights into a potential breast cancer therapeutic. Cellular Oncology. 2013;36(6):449-57. http://www.ncbi.nlm.nih.gov/pubmed/24081907

  11. Mirjolet C**, Papa AL**, Crehange G, Raguin O, Seignez C, Paul C, Truc G, Maingon P, Millot N*. The radiosensitization effect of titanate nanotubes as a new tool in radiation therapy for glioblastoma: a proof-of-concept. Radiother Oncol. 2013;108(1):136-42. http://www.ncbi.nlm.nih.gov/pubmed/23647757

  12. Papa AL, Basu S, Sengupta P, Banerjee D, Sengupta S*, Harfouche R*. Mechanistic studies of Gemcitabine-loaded nanoplatforms in resistant pancreatic cancer cells. BMC Cancer. 2012;12:419. http://www.ncbi.nlm.nih.gov/pubmed/22998550

  13. Paraskar A, Soni S, Roy B, Papa AL, Sengupta S*. Rationally designed oxaliplatin-nanoparticle for enhanced antitumor efficacy. Nanotechnology. 2012;23(7):075103. http://www.ncbi.nlm.nih.gov/pubmed/22275055

  14. Papa AL**, Maurizi L**, Vandroux D, Walker P, Millot N*. Synthesis of Titanate Nanotubes Directly Coated with USPIO in Hydrothermal Conditions: A New Detectable Nanocarrier. The Journal of Physical Chemistry C. 2011;115(39):19012-17. http://dx.doi.org/10.1021/jp2056893

  15. Papa AL, Millot N*, Saviot L, Chassagnon R, Heintz O. Effect of Reaction Parameters on Composition and Morphology of Titanate Nanomaterials. The Journal of Physical Chemistry C. 2009;113(29):12682-89. http://dx.doi.org/10.1021/jp903195h

  16. Saviot L, Netting CH, Murray DB, Rols S, Mermet A, Papa AL, Pighini C, Aymes D, Millot N*. Inelastic neutron scattering due to acoustic vibrations confined in nanoparticles: Theory and experiment. Physical Review B. 2008;78(24):245426. http://prb.aps.org/abstract/PRB/v78/i24/e245426

 

 

Publications

Book Chapters

  1. Maurizi L, Papa AL, Boudon J, Sudhakaran S, Pruvot B, Vandroux D, Chluba J, Lizard G, Millot N. Toxicological Risk Assessment of Emerging Nanomaterials: Cytotoxicity, Cellular Uptake, Effects on Biogenesis and Cell Organelle Activity, Acute Toxicity and Biodistribution of Oxide Nanoparticles. Unraveling the Safety Profile of Nanoscale Particles and Materials-From Biomedical to Environmental Applications. 2018;InTech. https://www.intechopen.com/books/unraveling-the-safety-profile-of-nanoscale-particles-and-materials-from-biomedical-to-environmental-applications/toxicological-risk-assessment-of-emerging-nanomaterials-cytotoxicity-cellular-uptake-effects-on-biog

  2. Boudon J, Papa A-L, Paris J, Millot N. Titanate nanotubes as a versatile platform for nanomedicine. Nanomedicine. 2014;One Central Press:404-29. http://www.onecentralpress.com/wp-content/uploads/2014/11/CHAPTER-16-NM-09-LATEST.pdf